High-Order Harmonic Generation and Molecular Orbital Tomography: Characteristics of Molecular Recollision Electronic Wave Packets

We investigate the orientation dependence of molecular high-order harmonic generation (HHG) both numerically and analytically. We show that the molecular recollision electronic wave packets (REWPs) in the HHG are closely related to the ionization potential as well as the particular orbital from which it ionized. As a result, the spectral amplitude of the molecular REWP can be significantly different from its reference atom (i.e., with the same ionization potential as the molecule under study) in some energy regions due to the interference between the atomic cores of the molecules. This finding is important for molecular orbital tomography using HHG[Nature \textbf{432}, 867(2004)].Comment: 4 pages, 4 figure

Fusion for Component based Face Recognition

This paper proposes a practical way to realize the diversity in face recognition system for performance improvement by fusing the classification results from the components (characteristic regions such as eyes, nose and mouth) and from the whole face image, instead of concatenating the face feature and the modular features for a single classifier. The extracted sub-images are not totally independent from the face image, but the experiments show that the fused result is improved from the recognition result based on the face or components alone. The fusion is implemented and compared at both score level and decision level. Communication resources are preserved between the sensor and fusion point in decision level fusion at the expense of performance, and the selection of which fusion scheme to use depends on the system resources and performance requirement

Hyperhomocysteinemia exacerbates cisplatin-induced acute kidney injury in mice by upregulating the expression of endoplasmic reticulum stress protein

Purpose: To determine the effect of hyperhomocysteinemia on cisplatin-induced acute kidney damage, as well as the mechanism involved. Methods: Forty-eight healthy mice were assigned to control and model groups, having 16 and 32 mice, respectively. Cisplatin was intraperitoneally given to model mice at a level of 20 mg/kg. Serum levels of homocysteine (Hcy), BUN and creatinine (Scr) were measured in each group, and changes in kidney coefficient were calculated. Changes in levels of glucose regulatory protein 78 (GRP78) and cysteinedependent aspartate-directed protease-12 (Caspase-12) were determined with immunohistochemistry and Western blot assay. Results: Serum Hcy, BUN, Scr, renal coefficient, and the expression levels of GRP78 and Caspase-12 in kidney of model mice were markedly elevated, relative to control values (p < 0.05). However, relative to model mice, serum Hcy, BUN, Scr, renal coefficient, apoptosis level of renal tubular epithelial cells, and GRP78, Caspase-12 expression levels in renal tissue were significantly increased in the highmethionine intervention group (p < 0.05). Conclusion: Cisplatin induces acute renal injury in mice. Hyperhomocysteinemia may aggravate cisplatin-induced acute renal injury by upregulating the expression of endoplasmic reticulum stress protein

Detection and localization of continuous gravitational waves with pulsar timing arrays: the role of pulsar terms

A pulsar timing array is a Galactic-scale detector of nanohertz gravitational waves (GWs). Its target signals contain two components: the `Earth term' and the `pulsar term' corresponding to GWs incident on the Earth and pulsar respectively. In this work we present a Frequentist method for the detection and localization of continuous waves that takes into account the pulsar term and is significantly faster than existing methods. We investigate the role of pulsar terms by comparing a full-signal search with an Earth-term-only search for non-evolving black hole binaries. By applying the method to synthetic data sets, we find that (i) a full-signal search can slightly improve the detection probability (by about five percent); (ii) sky localization is biased if only Earth terms are searched for and the inclusion of pulsar terms is critical to remove such a bias; (iii) in the case of strong detections (with signal-to-noise ratio $\gtrsim$ 30), it may be possible to improve pulsar distance estimation through GW measurements.Comment: 12 pages, 9 figures, typos corrected. To match the published version. Code implementing this method is available at the PPTA Wiki pag

Measurement of Charge Distributions in a Bubbling Fluidized Bed Using Wire-Mesh Electrostatic Sensors

In order to maintain safe and efficient operation of a fluidized bed, electrostatic charges in the bed should be monitored continuously. Electrostatic sensors with wire-mesh electrodes are introduced in this paper to measure the charge distribution in the cross section of the fluidized bed. A Finite Element Model is built to investigate the sensing characteristics of the wire-mesh sensors. In comparison with conventional electrostatic sensors, wire-mesh sensors have higher and more uniform sensitivity distribution. Based on the induced charges on the electrodes and the sensitivity distributions of the sensors, the charge distribution in the cross section of the fluidized bed is reconstructed. However, it is difficult to directly measure the induced charges on the electrodes. A charge calibration process is conducted to establish the relationship between the induced charge on the electrode and the electrostatic signal. Experimental studies of charge distribution measurement were conducted on a lab-scale bubbling fluidized bed. The electrostatic signals from the wire-mesh sensors in the dense phase and splash regions of the bed for different fluidization air flow rates were obtained. Based on the results obtained from the charge calibration process, the estimated induced charges on the electrodes are calculated from the Root Mean Square values of the electrostatic signals. The characteristics of the induced charges on the electrodes and the charge distribution in the cross section under different flow conditions are investigated, which proves that wire-mesh electrostatic sensors are able to measure the charge distribution in the bubbling fluidized bed

Light induced non-volatile switching of superconductivity in single layer FeSe on SrTiO3 substrate

The capability of controlling superconductivity by light is highly desirable for active quantum device applications. Since superconductors rarely exhibit strong photoresponses, and optically sensitive materials are often not superconducting, efficient coupling between these two characters can be very challenging in a single material. Here we show that, in FeSe/SrTiO3 heterostructures, the superconducting transition temperature in FeSe monolayer can be effectively raised by the interband photoexcitations in the SrTiO3substrate. Attributed to a light induced metastable polar distortion uniquely enabled by the FeSe/SrTiO3 interface, this effect only requires a less than 50 µW cm−2 continuous-wave light field. The fast optical generation of superconducting zero resistance state is non-volatile but can be rapidly reversed by applying voltage pulses to the back of SrTiO3substrate. The capability of switching FeSe repeatedly and reliably between normal and superconducting states demonstrate the great potential of making energy-efficient quantum optoelectronics at designed correlated interfaces

Dexmedetomidine reduces inflammation in mice with acute pancreatitis by inhibiting NLRP3 inflammasome and sympathetic nerve activity

Purpose: To study the anti-inflammatory influence of dexmedetomidine (DEX) in mice with acute pancreatitis (AP), and to determine the underlying mechanism.Methods: A total of 75 healthy ICR male mice were randomly divided into control, mild acute pancreatitis (MAP), MAP+DEX, severe acute pancreatitis (SAP), and SAP+DEX groups, with 15 mice/group. Blood levels of inflammatory factors (TNF-α and IL-1β) and norepinephrine were assayed ineach group. Western blotting was used to assay the protein expressions of NLRP3 and norepinephrine transporter (NET) in the pancreatic tissue of each group.Results: The levels of inflammatory factors in the MAP+DEX group were markedly lower than those in the MAP group after 10 h of MAP induction (p < 0.01). Mice in MAP+DEX group had significantly lower expression of NLRP3 in pancreatic tissue, and significantly higher NET protein level, relative to the MAP mice. Following 10 h of SAP, concentrations of the inflammatory factors and the pancreatic expression of NLRP3 were lower in SAP+DEX-treated mice than in SAP mice, while NET protein was significantly higher in SAP mice (p < 0.01).Conclusion: DEX reduces the expressions of inflammation-related factors TNF-α and IL-1β, and inhibits inflammatory response in mice with AP via downregulation of NET protein expression via inhibition of NLRP3 and early sympathetic events. Keywords: Dexmedetomidine, NLRP3 inflammasome, Sympathetic nerve, Acute pancreatitis, Inflammatory respons

Design of multifunctional color routers with Kerker switching using generative adversarial networks

To achieve optoelectronic devices with high resolution and efficiency, there is a pressing need for optical structural units that possess an ultrasmall footprint yet exhibit strong controllability in both the frequency and spatial domains. For dielectric nanoparticles, the overlap of electric and magnetic dipole moments can scatter light completely forward or backward, which is called Kerker theory. This effect can expand to any multipoles and any directions, re-named as generalized Kerker effect, and realize controllable light manipulation at full space and full spectrum using well-designed dielectric structures. However, the complex situations of multipole couplings make it difficult to achieve structural design. Here, generative artificial intelligence (AI) is utilized to facilitate multi-objective-oriented structural design, wherein we leverage the concept of "combined spectra" that consider both spectra and direction ratios as labels. The proposed generative adversarial network (GAN) is named as DDGAN (double-discriminator GAN) which discriminates both images and spectral labels. Using trained networks, we achieve the simultaneous design for scattering color and directivities, RGB color routers, as well as narrowband light routers. Notably, all generated structures possess a footprint less than 600x600 nm indicating their potential applications in optoelectronic devices with ultrahigh resolution

Novel and predominant pathogen responsible for the enterovirus-associated encephalitis in eastern China

Enteroviruses (EV) have been increasingly identified as the causative agent for unknown etiological encephalitis in many parts of the world, but the long period surveillance for enterovirus-associated encephalitis (EAE) was not reported in China. From 2002-2012 in Zhejiang, Coxsackieviruses A9, B1, B2, B3, B4, B5; and echoviruses 3, 4, 6, 9, 14, 25, 30 were detected from the unknown etiological encephalitis cases, with coxsackievirus B4 been identified here for the first time. From 2002-2004 and 2010-2012, echovirus 30 was found to be the periodically predominant serotype for in the EAE. The molecular typing results showed that all the EV isolates from this study belonged to the human EV B (HEV B) family and were distributed in three clusters